Bipolar Disorder

Mania With Depressive Symptoms: A Pathophysio-Logical Review

Key messages ● Bipolar disorder (BD) is a common, complex, and costly psychiatric illness that can be devastating for the affected individual and their families. Suicide is an important risk across the life span of bipolar patients. ● Accurate diagnosis is not easy, particularly in mixed states. Psychotic symptoms may suggest schizophrenia, and a major […]

The International Society Of Affective Disorders

Join us at the Intercontinental in Berlin for the 7th Biennial Congress of The International Society of Affective Disorders, 28th – 30th April, 2014.

A very warm Welcome to our new Advisory board member – Krassen Nedeltchev

Don’t Overreach For Subthreshold Pediatric Bipolar Disorder

When youths get referred for help with symptoms that don’t quite meet diagnostic criteria for bipolar illness, there’s a 50-50 chance they’ll progress to a diagnosis of bipolar disorder I or II within 7 years. The odds are a coin toss. The risk logically might be even lower in general clinical settings than in this […]

Medical Comorbidity Affects Disease Course in Bipolar Disorder

The burden of comorbid medical illness is high, and is linked to increased prescribing of psychotropic drugs, in patients with bipolar I and II disorder, based on findings from the Lithium Treatment – Moderate Dose Use Study, or LiTMUS.

Novel Antipsychotic Treats Acute Mania in Bipolar Disorder

The novel atypical antipsychotic drug cariprazine is effective for the treatment of acute mania associated with bipolar I disorder, according to findings from a randomized, placebo-controlled phase III study.

Is My Child ‘Bipolar’?

We all understand that bipolar disorder is a mood disorder, characterized by periods of depression and mania, that many of us have seen in adults.

Adjunctive Lithium Reduces Use of Newer Antipsychotics in Bipolar

In a 6-month study, the use of adjunctive moderately dosed lithium to optimized treatment in patients with bipolar disorder was well tolerated yet did not lead to improved outcomes or decreased suicidality. However, use of adjunctive lithium resulted in a significant reduction in the use of second-generation antipsychotics.