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C9orf72-Associated Frontotemporal Dementia And Psychosis

Frontotemporal dementia (FTD) is a progressive neurodegenerative disease. About 30-40% of the cases have a positive family history, and genetic mutations are identifiable in an increasing proportion of cases. Although psychosis in FTD has been recognized for many years, it has not been taken as a key feature, and has not been included in the clinical diagnostic criteria.

This paper assesses the prevalence and characteristics of psychotic symptoms in…

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