Gothenburg, Sweden, 16 May 2018- The main results of the European WAKE-UP trial will be/have been presented on 16 May at the European Stroke Organisation Conference (ESOC). At the same time, the trial results will be/have been published in the New England Journal of Medicine. The trial demonstrates that MRI-selected stroke patients with unknown time […]
Leaving A Legacy Of Stroke In Europe: A Community Of Dedicated Professionals Is Changing The Face Of Stroke In Europe
Time is of the essence in the treatment of acute stroke; however, there are wide variations, across and within countries, in the ability to hospitalize, scan, diagnose, and treat acute stroke patients rapidly within the accepted time window of 4.5 hours. Door-to-needle (DTN) time is an important performance indicator that illustrates the speed and operational […]
This symposium acknowledged considerable variation across European in-hospital stroke services in their level of expertise, facilities available for rapid neuroimaging, and access to treatment interventions for acute stroke patients. Stroke neurologists face the dilemma of deciding whether to dispatch acute stroke patients to a highly specialised comprehensive stroke centre, or to the nearest available centre. […]
The Pipeline Embolization Device (PED) has become a routine first-line interventional option for treatment of intracranial aneurysms; however, thromboembolic complications are the main adverse events with flow diversion interventional procedures. A new, third generation version of the PED, the Pipeline Flex™ Embolization Device with Shield Technology™ (PFEDST), is now available with…
“Time is brain” is a concept that perfectly encapsulates the need for swift action when stroke strikes. The sooner stroke symptoms are realised, the sooner the person gets the care they need, the greater the chances for survival and life with fewer disabilities. What happens in Europe is that a person who has a stroke […]
Cardiovascular diseases, including stroke, are the leading cause of death in the European Union (EU), responsible for more than 4 million deaths in 2013 and accounting for 45% of all deaths. Coronary heart disease (CHD) and stroke account for the majority CVD-related deaths, with 1.8 million deaths from CHD and 1 million from stroke annually. […]
Novel Stroke Prophylaxis Strategies: When Should Device-Based Cardiac Occlusion Therapies Be Considered?
Oral anticoagulation (OAC) is the established therapy to prevent ischemic stroke in high-risk patients with atrial fibrillation (AF) and it reduces the threat of recurrence in those who had a cardioembolic stroke. However, OAC is associated with a substantial risk of major bleeding. Therefore, device-based occlusion therapies including left atrial appendage occlusion (LAAO) and patent […]
Acute Ischaemic Stroke (AIS) is the second cause of death and disability in Europe. Mechanical thrombectomy has proven efficacy in the management of patients with large vessel occlusions. It brings hope to the treatment of AIS, but the development of this technique is still ongoing. Technological developments, especially thromboaspiration, offer promising results. The need for the timely identification, transfer, and treatment of […]
The Angels (Acute-Networks StrivinG For ExceLlence In Stroke) Initiative: Solving A Problem By Giving Physicians The Tools They Need To Create A Solution
Stroke can be a devastating event, not only for the victims, but also for their families, friends, work colleagues, and carers. The burden of stroke in terms of absolute numbers and number of disability adjusted life years (DALYs) is increasing worldwide and is impacting health services on a global scale. Despite an earlier reluctance to […]
Stroke is a sudden loss of brain function due to disturbance in the cerebral blood supply with symptoms lasting at least 24 hours or leading to death with vascular background as its only cause. Stroke can be caused either by rupture of a blood vessel or…
Minimizing The Risk Of Hemorrhagic Stroke During Oral Anticoagulant Therapy For Atrial Fibrillation: The Neurologist’s Perspective
Until recently, warfarin has been the gold standard for reducing stroke risk and mortality in patients with atrial fibrillation (AF). The key goals of antithrombotic treatment are the primary and secondary prevention of ischemic stroke and systemic embolism while minimizing…
Daniel Prefasi Gomar MD; Patricia Martínez-Sánchez , MD, PhD; Exuperio Díez-Tejedor, MD, PhD, FAHA, FESO, FANA. Department of Neurology and Stroke Centre La Paz University Hospital. Autonoma of Madrid University. IdiPAZ Health Research Institute Paseo de la Castellana 261, 28046, Madrid, Spain. Telephone number: +34 91 7277444 Fax number: +34 913581403 e-mail: firstname.lastname@example.org; email@example.com […]
Dr Clare Walton, Research Communications Officer at The Stroke Association Stroke is the leading cause of complex adult disability in the
Patients who become depressed after having had a stroke are four times more likely to die than those who have not had a stroke and who are not depressed. Results of a large 21-year follow-up study stress the importance of depression screening in poststroke care, according to Dr. Amytis Towfighi, who will present her data […]
Prof.Dr.C.Dettmers Kliniken Schmieder Konstanz, Konstanz, Germany; Faculty of Psychology, University Konstanz, Konstanz, Germany.
Marc Fisher, MD (pictured below) Department of Neurology, University of Massachusetts School of Medicine Gregory W. Albers, MD Stanford University School of Medicine
Oral relaxin therapy resulted in significantly improved cognitive and functional recovery in poststroke patients participating in a randomized controlled trial.
Numerous muscles are involved and use coordination just to perform simple actions like picking up a pen. For instance, the eyes and head need to turn towards the object, the hand needs to reach towards the pen and the fingers need to pick it up.
When used as a first-line choice for the treatment of acute ischemic stroke secondary to large artery occlusion, the Solitaire FR revascularization device was safe and offered good recanalization rates and clinical outcomes, a multicenter study showed. The Solitaire FR device, which mechanically removes blood clots from blocked vessels, received CE Mark approval in Europe […]
A study indirectly comparing three oral anticoagulant drugs – dabigatran, rivaroxaban, and apixaban – has revealed potential differences among the agents in their relative efficacy and safety when used for stroke prevention in atrial fibrillation.
A thrombus retrieval device for use in patients experiencing an acute ischemic stroke has been cleared for marketing in the United States by the Food and Drug Administration, the manufacturer announced on Aug. 13. The device will be marketed as the “Trevo Pro Retriever,” according to the statement issued by Stryker Neurovascular. Courtesy Stryker Neurovascular
Interim results from an ongoing study demonstrated that that a higher pretreatment Alberta Stroke Program Early CT Score on computed tomography angiogram images is associated with better outcome following endovascular therapy. “There is no standard imaging approach for endovascular therapy patient selection,” Dr. Donald Frei said at the annual meeting of the Society of Neurointerventional […]
Rankings of hospital performance in treating acute ischemic stroke must take into consideration the severity of each case, or the rankings will be extremely inaccurate, researchers say in the July 18 issue of JAMA. Unfortunately, the rankings that are currently used by accreditation organizations, the Centers for Medicare and Medicaid Services (CMS), and other payers […]
Maternal hypertension and intrapartum fever increase the risk for ischemic stroke in infants, a large retrospective analysis suggests. Gestational diabetes, a known risk factor for maternal hypertension and neonatal hypoglycemia, does not increase stroke risk. “Additional research is needed to determine the mechanism underlying these associations and to develop effective preventive methods for high-risk infants,” […]
Statins are beneficial in women for the secondary prevention of some cardiovascular events, but they don’t appear to be any better than placebo at preventing stroke or all-cause mortality, according to a meta-analysis reported in the June 25 issue of Archives of Internal Medicine.
Oral contraceptives containing low- or very low-dose estradiol raised the risks of thrombotic stroke and myocardial infarction by a factor of 1 to 2 in a large Danish cohort study. The results were published in the June 14 issue of the New England Journal of Medicine.
Nearly half of elderly patients who have an ischemic stroke also have atrial fibrillation, based on a review of 527 stroke patients aged 75 or older at a single U.S. center.
The American Stroke Association is developing a host of new guidelines and statements, including a consensus statement on the definition of stroke and a scientific review of new anticoagulants. The first new guideline – on the Management of Aneurysmal Subarachnoid Hemorrhage (SAH) – is complete and has been submitted for publication, said Dr. Colin Derdeyn, […]
Levels of air pollution that fall within the amounts deemed safe in current U.S. standards for air quality were associated with a significant increase the risk for acute ischemic stroke after short-term exposure and accelerated cognitive decline after long-term exposure in two separate studies. Previous studies of the effects of ambient fine particulate matter air […]
Two new risk assessment scores predicted the likelihood of a symptomatic intracranial hemorrhage after ischemic stroke treatment with more than 70% accuracy.
A granulocyte colony-stimulating drug did not protect brain tissue or improve functional outcomes after ischemic stroke.
The potential advantages of tenecteplase, a modified form of tissue plasminogen activator engineered to outperform the native molecule, finally shone through for treating patients with acute ischemic stroke. A head-to-head comparison of tenecteplase against recombinant tissue plasminogen activator (TPA; alteplase) showed that the modified molecule produced better reperfusion and better clinical recovery 24 hours after […]
When results from a major trial with more than 900 patients failed to show that closure of a patent foramen ovale in patients who had a cryptogenic stroke worked better than medical therapy for preventing a future stroke, some experts suggested that the problem was patient selection. Researchers now have evidence that this explanation was […]
Pediatric stroke survivors had an absolute risk of 39% for developing epilepsy in the 10 years following their stroke in a review of 371 patients in Northern California. Two factors significantly boosted a child’s risk of developing epilepsy following a stroke: A seizure at the time of stroke, and a neurologic deficit at the time […]
An elevated Framingham Risk Score identified recent ischemic stroke patients at high risk for a myocardial infarction or vascular death over the next 2 years, in a retrospective analysis of data from more than 2,500 stroke survivors without documented coronary heart disease. If prospective study results confirm this finding, it could establish the Framingham Risk […]
“Drip and ship” is a safe way to manage patients with acute ischemic stroke, according to results from two separate studies. A review of 145 ischemic stroke patients who began receiving an intravenous infusion of tissue plasminogen activator (TPA) at a community hospital, followed by transport to a regional primary stroke center, showed a 63% […]
An investigational clot-retrieval device completely recanalized blocked cerebral arteries, improved neurologic outcomes, and significantly reduced mortality from acute ischemic stroke more often than did the widely used Merci device in a randomized, open-label trial. The SWIFT (SOLITAIRE-FR With the Intention for Thrombectomy) study intended to randomize 200 patients with ischemic stroke to treatment with either […]
The extra time needed for CT perfusion imaging in patients with an acute ischemic stroke may not be warranted, based on a retrospective analysis of 418 patients treated at nine U.S. tertiary stroke centers. The analysis showed that the outcomes in patients assessed using CT perfusion (CTP) were very similar to those in patients worked […]
There may be a correlation between infection and stroke in children, according to research presented at the International Stroke Conference. Acute infection is considered to be a risk factor for stroke in adults, so researchers from the University of California, San Francisco, decided to study whether it might also be a potential risk in children, […]
Tick, tick, tick. It’s a familiar sound to neurologists, who have grown accustomed to watching the clock as they hurry to get tissue plasminogen activator on board in ischemic stroke patients. If Dr. Steven Cramer proves correct, a second timer may soon be ticking, this one measuring in days or weeks a limited “golden” period […]
A cardiac rehabilitation program can help cerebrovascular-disease patients as much as it helps patients with cardiac disease, based on results from 89 patients treated in a Canadian pilot program. “Patients suffering a nondisabling stroke or TIA [transient ischemic attack] gain the same, if not better, outcomes from being part of a multifactorial, risk-reduction program traditionally […]
1) Indications and outcomes of the Pipeline™ Shield device in treating small aneurysms: a single center experience. Istvan Szikora, Budapest, Hungary 2) Clinical experience with Pipeline™ Flex with Shield technology™ and follow-up data Saleh Lamin, Birmingham, United Kingdom 3) Sizing always matter for optimal Pipeline™ placement Mohamed Aggour, Saint-Etienne, France
Boehringer Ingelheim ESOC 2018 – Stroke Prevention and Treatment: New Insights Into NOACS and Reversal
1) Introduction: Stroke prevention and treatment: new insights into NOACs and reversal Martin Grond, Germany 2) Stroke prevention in AF: how can we optimize anticoagulation? Danilo Toni, Italy 3) Stroke treatment: can dabigatran reversal improve outcomes? Martin Grond, Germany 4) Embolic stroke of undetermined source (ESUS): concept and current treatment options Hans-Christoph Diener, Germany
What is the future for NOACs in Secondary Prevention of ESUS? – Christina Sjöstrand, Hans-Christoph Diener & George Ntaios
The European Accreditation Committee in CNS (EACIC) has granted 1 CME credits to the Round Table Discussion ‘What is the future for NOACs in secondary prevention of ESUS?’. June 2018 – November 2018 HOW TO OBTAIN CME CREDITS Participants requesting CME credits are required to complete the online evaluation form on the EACIC website […]
1) Patient Imaging Selection Criteria Greg Albers, USA 2) Solitaire Platinum – 1st year experience Markus Möhlenbruch, Germany 3) Atrial Fibrillation in Stroke Patients: Are You Looking Long Enough? Martin Köhrmann, Germany 4) ITB Therapy for Post Stroke Spasticity – New Evidence for an Unmet Need Geoffrey Cloud, Australia
1) Strategic planning of stroke unit coverage and quality improvement, the Austrian experience Julia Ferrari, Vienna 2) Quality monitoring to improve acute stroke care on a national level, the Czech experience Ales Tomek, Prague 3) Creating the link between stroke ready hospitals and emergency medical services, the Slovakian experience Matej Polák, Komarno 4) Simulation training […]
The European Accreditation Committee in CNS (EACIC) has granted 1 CME credit to the Round Table Discussion ‘Embolic Stroke of Undetermined Source (ESUS)’. April 2018 – September 2018 HOW TO OBTAIN CME CREDITS Participants requesting CME credits are required to complete the online evaluation form on the EACIC website www.eacic.eu. Please follow the below steps […]
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Minimizing The Risk Of Haemorrhagic Stroke During Oral Anticoagulant Therapy For Atrial Fibrillation: The Neurologists’ Perspectives
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In-hospital management of acute ischaemic stroke: how can we do better?
New ESC Guidelines For Stroke Prevention In Atrial Fibrillation. The Cardiologist And The Neurologists Perspective
New ESC Guidelines for Stroke Prevention in Atrial Fibrillation. The Cardiologist and the Neurologists Perspective HD Supported by an independent educational grant from
A review of a stroke registry shows that it may be safe to give clot-busting therapy to “wake-up” stroke patients who have the same clinical and imaging features as those of patients who are traditionally considered eligible for the therapies. Clinicians have traditionally shied away from giving clot-busters to patients who have stroke symptoms upon […]
Patients with a very low or a very high hematocrit are at higher risk for death after a stroke, and anemic patients are at greatest risk, according to a study presented at the International Stroke Conference sponsored by the American Heart Association on Feb. 2. Previous studies have shown that extremes of hematocrit increase mortality […]
Memory is already impaired years before a stroke occurs, declining most rapidly in people destined to suffer a fatal stroke, according to a population-based study of more than 11,000 people. “For every year that passed [after age 50 years], those who survived a stroke lost their memory at twice the rate as controls. And for […]